BiS is part of the Biomedical Engineering Department at TU/e. Research at BiS is dedicated to understanding and applying basic cell biological principles at the biointerfaces especially for regenerative medicine. The research program is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology to streamline the wealth of biological knowledge to real clinical applications.
Cell biology, computational approaches, and material development are the three key fields of science that we focus our research on at BiS. To find out more, have a look here:
Read this short assay by Jan de Boer entitled: ” On mixing people and ideas - a brief history of the TopoChip”
Our collaborative work conducted in University of Nottingham in the laboratories of Morgan Alexander and Amir Ghaemmaghami with our TopoChip platform just accepted in Advanced Science. Congratulations to all participating authors. The article is about using topography to control human monocyte attachment and macrophage differentiation to induce pro-inflammatory, anti-inflammatory or regulatory immune responses . You can reach the original article here where you will be inspired once again how topographical cues direct cell fate to provide a platform to design ‘immune-instructive’ biomaterials for implantable medical devices to fight against foreign body rejection.
