Jan is interested in the molecular complexity of cells and how molecular circuits are involved in cell and tissue function. With a background in mouse and Drosophila genetics, he entered the field of biomedical engineering in 2002 and has since focused on understanding and implementing molecular biology in the field of tissue engineering and regenerative medicine. His research is characterized by a holistic approach to both discovery and application, aiming at combining high throughput technologies, computational modeling and experimental cell biology to streamline the wealth of biological knowledge to real clinical applications. His research is defined by strong interdisciplinary collaborations through his big network. He is the former chair of the Netherlands Society for Biomaterials and Tissue Engineering and founder and former chair of the MosaCell platform for patient-derived stem cell research. He brought transcriptomics and computational sciences into his research established a data repository cBIT and his current team comprises both experimental and computational scientists. Jan is a full professor at Biomedical Engineering Department, Eindhoven University of Technology (TU/e), chair of BiS, Biointerface Science in Regenerative Medicine since 2018. He was a founding member of the Merln Institute for Technology-Inspired Regenerative Medicine, Maastricht University and chair of cBITE, Cell Biology Inspired Tissue Engineering Lab between 2014-2018 and worked as an associate professor at the MIRA Institute for Biomedical Technology, University of Twente between 2004-2014.