Topographic approach to address the problem of foreign body response in glaucoma drainage devices
Phani comes from southern part of India where he did his bachelors in biotechnology in 2011. He got interested in the inter disciplinary scope of the field while working at a company where he was a part of the project to test active drug efficacy from different phytochemical plant extracts for anti cancerous activity. In 2013, he started his masters in university of Tuebingen (Germany) in biomedical technologies where he took implantology as one of his specialization with focus on biomaterials which really fascinated him. As a part of his thesis, he did his project titled “In-vitro evaluation of small molecules for anti microbial activity in gram negative bacteria” which focuses on the characterisation of active hits from high throughput screening. As a part of his Ph.d, he will be focusing his research on performing high throughput screening of topographies to address the fibrotic response in glaucoma shunt devices used in treatment of glaucoma to reduce the intra ocular pressure. The objective of the project is to develop surface topographies with anti-fibrotic properties that can avoid implant failure.
A short poster presentation of Phani's current research can be found here.