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Streggi Vandersteene

Streggi Vandersteene

BiS Members
Streggi Vandersteene

Streggi Vandersteene

BiS Members
Streggi Vandersteene

Streggi Vandersteene

BiS Members
Streggi Vandersteene

Streggi Vandersteene

Streggi graduated from KU Leuven with a bachelor’s degree in Pharmaceutical Sciences and master’s degree in Drug Development. The fascinating thing about research that intrigues her the most is deciphering complex molecular mechanisms and their biological functions. During an exchange with the Medical University of Vienna, she studied how the invasive potential of macrophages is affected by the neurometabolic disease X-linked adrenoleukodystrophy. The aim of this study was to elucidate the role of very long-chain fatty acids in proinflammatory macrophage activation, as well as to identify whether elevated levels of these fatty acids could increase macrophage invasiveness through enhanced cytoskeleton remodeling. In December 2022, she joined the BioInterface Science group of Prof. Jan de Boer at Eindhoven University of Technology. As part of her PhD, her research focuses on the molecular mechanism by which biomaterials control the phenotype of cells that come into contact with them. Emphasis is placed on the role of integrin-mediated signaling in the phenotypic control of fibroblasts and macrophages. The aim of this research is to improve the interaction of medical implants with the human body, while controlling the foreign body response to prevent implant failure.