Laurence Burroughs (University of Nottingham) carried out his undergraduate studies at The University of York where he received his MChem degree in 2007. After his undergraduate studies he continued at The University of York to carry out his PhD research under the supervision of Dr. Paul A. Clarke, investigating plausibly prebiotic routes to carbohydrates. In 2011 Laurence received his PhD in Organic Chemistry, after which he spent a short period at ACM Global Laboratory, York as an analytical scientist. In 2013 he joined The University of Nottingham to work with Prof. Simon Woodward developing synthetic routes to novel organic semiconductors. In 2016 Laurence moved to work on biomaterials development utilising polymer microarray screening with Prof. Morgan Alexander.
Laurence’s current research aims to enhance our understanding of material-cell interactions in an effort to develop highly optimised biologically-relevant systems. He investigates the impact of both chemistry and topography on cell response in a high-throughput manner by combining a range of substrate chemistries with the surface patterning approach of TopoChip technology. Of particular interest to Laurence’s research are systems that enhance the osteogenic differentiation of mesenchymal stem cells and those that promote the growth and maturation of cardiomyocytes.
- Aurélie Carlier, 2018, Assistant Prof at cBITE
- Dennie Hebels, 2018, Project Manager at cBITE
- Marloes Kamphuis, 2018, Lab Manager at cBITE
- Naida Roumans, 2018, Lab Technician at cBITE
- Nick Beijer, 2018, PhD student: Topographically enhanced cell culture systems to induce and monitor mechanobiology.
- Frits Hulshof, 2016, PhD student: Topochip: Technology for Instructing Cell Fate and Morphology via Designed Surface Topography.
- Jenny Brinkmann, 2016, PhD student: Dynamic bioactive surfaces for cells using cucurbiturils.
- Maqsood (Max) Ahmed, 2014, postdoc: High-throughput screening of fiber spun scaffolds.
- Anouk Mentink, 2014, research technician and lab manager.
- Eelco Fennema, 2014, PhD student: An analysis of trauma and its solutions in bone tissue engineering.
- Bach Le Quang, 2014, PhD student:Decellularized cartilage matrix as an alternative for demineralized bone matrix.
- Nathalie Groen, 2014, PhD student: High throughput screening of bone graft materials.
- Vanessa LaPointe, 2014, postdoc: Molecular biology in 3D.
- Karolina Janeczek, 2013, PhD student: Endothelial differentiation of mesenchymal stem cells.
- Hemant Unadkat, 2012, PhD student: The effect of topography on cell behaviour.
- Joyce Doorn, 2012, PhD student: Paracrine signaling of human mesenchymal stem cells.
- Anindita Ganguly, 2012, PhD student: Clinical translation of bone tissue engineering.
- Ana Barradas, 2012, PhD student: Molecular mechanism of osteo-induction.
- Hugo Andre Alves, 2010, PhD student, Ageing and human mesenchymal stem cells.
- Jun Liu, 2009, PhD student, Bioluminescent imaging in tissue engineering.
- Jojanneke Jukes, 2009, PhD student, Embryonic stem cells in cartilage tissue engineering.
- Hugo Fernandes, 2009, PhD student and postdoc,The role of extracellular matrix in bone tissue engineering.
- Ram Siddappa, 2008, PhD student, Protein kinase A signaling in bone tissue engineering.
- Sanne Both, 2008, PhD student, Mouse embryonic stem cells in bone tissue engineering.
- Ruud Licht, 2007, research technician, Target discovery for bone-regeneration.
- Floris Honig,2018, Assessing the expression level of mechanical sensitive markers on topographical surfaces.
- Fred Zhaoji Shen,2018, Construction a computational model linking extracellular matrix properties to biomedical signaling pathway.
- Bianca Lourens,2018, Imaging capabilities to explore possibilities in distinguishing monocytes from healthy donors and monocytes exposed to proinflammatory factors.
- Adrián Seijas Gamardo,2018, Cell communication between mesenchymal stem cells and monocytes/macrophages
- Iris Wijnen,2018, Mechanotransduction pathways involved in topography-induced cell behavior
- Francesca Bolk,2018, Monocyte migration in response to proinflammatory factors
- Jingyun Wu,2018, the response of flexor tendon derived cells to TGF-β2 exposure,
- Rianne Helgers,2018, The response of flexor tendon derived cells to TGF-β2 exposure
- Zarina Nauryzgaliyeva, 2017: Braille code for cells: hMSCs protective response to cellular deformation induced by surface topographies
- Estela Arteaga, 2017: Study of the effect of topographies in human mesenchymal stem cells and cardiomyocyte size and proliferation
- Rika Reihs, 2017: Digitalizing life at the interface: Finding the missing links between biomaterial properties and biological pathways
- Ben van der Veer, 2017: Changing epigenetics with a Braille script for cells: The effect of micro topography on global histone acetylation and methylation in human mesenchymal stem cells
- Bram van Steen, 2017: Live Cell imaging reveals dynamic cell response to microstructured topographies
- Luc Sondorp, 2016: Gene regulatory effects of bone graft materials on osteoblasts
- Jéré van Lente, 2016: Topography screening with mesenchymal stem cells